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What would cause INR to rise?

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What would cause INR to rise?

A high INR level can happen when you take warfarin (Coumadin). Warfarin helps prevent blood clots. To do this, it slows the amount of time it takes for your blood to clot. This raises your INR level.

What medications increase warfarin?

Many of the drugs identified as potentiating warfarin’s effect are known inhibitors of CYP 2C9, including amiodarone, fluconazole, fluvastatin, fluvoxamine, isoniazid, lovastatin, phenylbutazone, and sertraline. Rifampin and secobarbital are both known inducers of CYP 2C9.

What drugs should not be taken with warfarin?

Common drugs that can interact with warfarin include:

  • Aspirin or aspirin-containing products.
  • Acetaminophen (Tylenol, others) or acetaminophen-containing products.
  • Antacids or laxatives.
  • Many antibiotics.
  • Antifungal medications, such as fluconazole (Diflucan)
  • Cold or allergy medicines.
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How do you feel when your INR is too high?

Signs of bleeding or a high INR are: Gums bleed when you brush your teeth. Coughing up blood. Vomit that looks like coffee grounds. Bruising in unusual areas or for unknown reasons.

Does vitamin K increase INR?

Vitamin K can change how warfarin works, which changes your INR. Vitamin K lowers your INR values. The lower your INR, the less time it takes for your blood to clot.

What drugs decrease INR?

Drugs that can decrease warfarin effect & lower INR in some pts include antacids, antihistamines, barbiturates, rifampin, sucralfate, trazodone, carbamazepine, cholestyramine, griseofulvin, haloperidol, oral contraceptives, penicillin, dicloxacillin, and nafcillin.

What painkillers are safe with warfarin?

If you need to take a painkiller while you’re taking warfarin it’s best to take paracetamol. Occasional painkilling doses of paracetamol should not affect your warfarin significantly.

How do I get my INR down?

How can I prevent an elevated INR?

  1. Have your INR measured regularly.
  2. If you take medicine, take it as directed.
  3. Eat the same amount of vitamin K daily to keep your INR stable.
  4. Limit alcohol.
  5. Do not smoke.
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How do you keep your INR stable?

To keep your INR stable and within the recommended range it is important to: Eat the same number of servings of high Vitamin K foods each week. A good rule is, the greener the plant the higher the Vitamin K level.

What foods should be avoided when taking blood thinners?

5 Things to Avoid If You’re On Blood Thinners

  • Leafy greens. Leafy greens like kale, spinach, Brussels sprouts and lettuce contain high amounts of vitamin K.
  • Green tea.
  • Cranberry juice.
  • Grapefruit.
  • Alcohol.

What do I do if my INR is too high?

How is an elevated INR treated?

  1. Vitamin K may be given to decrease your INR and bleeding.
  2. Blood components may be given during a transfusion to help stop your bleeding. Blood components are the parts of blood that help it to clot. Examples are clotting factors, platelets, and plasma.

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